HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 21552891, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 21552894 | HCID 21552894 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 21552891 | HCID 21552891 | 80.1% |
Reaction Steps
A solution of 1-cyano-8-(pyrrol-1-yl)isoquinoline (279 g.) in diethyl ether (7 liters) and pure chloroform (7 liters) saturated with anhydrous hydrogen chloride is kept at a temperature of between 0° and 5° C. for 72 hours. After extraction with ice-water (15 liters) followed by alkalinisation of the blood red acid solution thus obtained, 7-imino-7H-indolizino[5,6,7-ij]isoquinoline (223.4 g.) is obtained in the form of green-yellow needles melting at 201° C. with decomposition.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03946019 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-d47f77d81cc14f07b7f27c01866f64e3 |
| Source note | uspto-grants-1976_03 |