HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 21552894, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 68139828 | HCID 68139828 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21552894 | HCID 21552894 | 100.2% |
Reaction Steps
A mixture of 1-cyano-8-(pyrrol-1-yl)-2-toluene- p-sulphonyl-1,2-dihydroisoquinoline (446.2 g.) and sodium hydride (50% dispersion in mineral oil) (68.7 g.) in dimethylformamide (2,232 cc.) is kept at a temperature of about 20° C. for 16 hours. Crude 1-cyano-8-(pyrrol-1-yl)isoquinoline (261 g.), melting at 178° C., is thus obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03946019 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-e791db99d77540558ecd4601bd373bd2 |
| Source note | uspto-grants-1976_03 |