3-Methoxybenzaldehyde → HCID 68127996, compound

HRID 268007Notes

Reaction equation

HRID 268007 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=O.[CH2:11]([O:13][C:14](=[O:23])[CH2:15][C:16]([C:18]([O:20][CH2:21][CH3:22])=[O:19])=O)[CH3:12].[CH2:24]([O:26][C:27](=[O:32])/[CH:28]=[C:29](\[NH2:31])/[CH3:30])[CH3:25]>C(O)C>[CH2:24]([O:26][C:27]([C:28]1[CH:6]([C:5]2[CH:8]=[CH:9][CH:10]=[C:3]([O:2][CH3:1])[CH:4]=2)[C:15]([C:14]([O:13][CH2:11][CH3:12])=[O:23])=[C:16]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[NH:31][C:29]=1[CH3:30])=[O:32])[CH3:25]

Participants

5

Reactant 3

HCID 115693-MethoxybenzaldehydeHCID 66951Diethyl oxalacetateHCID 6437562-Butenoic acid, 3-amino-, ethyl ester, (2Z)-

Product 1

HCID 68127996HCID 68127996, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

27.2 g of 3-methoxybenzaldehyde, 38 g of oxalacetic acid diethyl ester and 26 g of β-aminocrotonic acid ethyl ester in 120 ccs of ethanol are heated to the boil overnight and evaporated in vacuo. Oil (orange).

Workup

  1. customevaporated in vacuo

Sources & evidence

ORD record
ord-a246fb22394041d286fb71c8c9c17542
Source dataset
uspto-grants-1976_03
Patent number
US03946027

Reaction notes

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