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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268066Generated: November 1, 2026

1,3-Cyclohexanedione → HCID 12391109, compound

https://huagongshe.com/reaction/268066

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-CyclohexanedioneHCID 10434—
Reactant2-NitrobenzaldehydeHCID 11101—
ReactantCarbamimidoyl-acetic acid ethyl esterHCID 4599837—
SolventEthanolHCID 702—
ProductHCID 12391109HCID 1239110969%

Reaction Steps

Upon heating a solution of 7.6 g of 2-nitrobenzaldehyde, 5.6 g of cyclohexane-1,3-dione and 6.5 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 2 hours, 2-amino-4-(2-nitrophenyl)-1,4,5,6,7,8-hexahydro-5-oxoquinoline-3-carboxylic acid ethyl ester of melting point 212°C (alcohol) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03946026
Source datasetuspto-grants-1976_03
ORD IDord-47df9a1496674908aba2eac1e9f07bf0
Source noteuspto-grants-1976_03