HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Cyclohexanedione → HCID 70635123, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Cyclohexanedione | HCID 10434 | — |
| Reactant | Isoquinoline-1-carbaldehyde | HCID 265306 | — |
| Reactant | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 70635123 | HCID 70635123 | — |
Reaction Steps
Upon heating a solution of 6.3 g of isoquinolin-1-aldehyde, 4.5 g of cyclohexane-1,3-dione and 5.2 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 2 hours, 2-amino-4-(isoquinol-1-yl)-1,4,5,6,7,8-hexahydro-5oxoquinoline-3-carboxylic acid ethyl ester of melting point 272°C (ethanol) is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03946026 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-51d1db5cfd0a4d648c5c37f3da30872c |
| Source note | uspto-grants-1976_03 |