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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268079Generated: October 31, 2026

1,3-Cyclohexanedione → HCID 3701157, compound

https://huagongshe.com/reaction/268079

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-CyclohexanedioneHCID 10434—
Reactant3-BromobenzaldehydeHCID 76583—
ReactantCarbamimidoyl-acetic acid ethyl esterHCID 4599837—
SolventEthanolHCID 702—
ProductHCID 3701157HCID 370115744%

Reaction Steps

Upon heating a solution of 9.3 g of 3-bromobenzaldehyde, 5.6 g of cyclohexane-1,3-dione and 6.5 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 8 hours, 2-amino-4-(3-bromophenyl)-1,4,5,6,7,8-hexahydro-5-oxoquinoline-3-carboxylic acid ethyl ester of melting point 255°C (ethanol) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03946026
Source datasetuspto-grants-1976_03
ORD IDord-3ee7b46b22ab476c97aa6f35177e217c
Source noteuspto-grants-1976_03