Potassium Hydroxide → HCID 54414057, compound

Participants

Reaction Steps

A mixture of 9.0 g (0.050 mole) of 5-(p-methylphenyl)-2-furonitrile, 3.75 g (0.054 mole) of hydroxylamine hydrochloride, 3.5 g (0.054 mole) of potassium hydroxide and 125 ml of absolute ethanol was refluxed for 2 hours and then cooled in an ice bath. The insoluble material was filtered and discarded. The filtrate was added to a mixture of ice/H2O and the resulting solid was filtered and stirred in 150 ml of refluxing hexane. The mixture was filtered hot and the solid was air dried to yield 7 g (65%). An analytical sample was prepared by recrystallizing a sample form hexane/Darco and drying in the vacuum pistol at the temperature of refluxing CHCl3, m.p. 139°-141°.

Provenance & Evidence