Nitric Acid → HCID 14251393, compound

Participants

Reaction Conditions

Reaction Steps

17,9 g (0.08 mol) of the 9-(β-cyanoethyl)-carbazole thus obtained were suspended in 108 ml glacial acetic acid in a three-necked flask equipped with a stirrer, condenser, thermometer and dropping funnel and a mixture of 13.5 ml glacial acetic acid and 6.75 ml 65% nitric acid were added dropwise, while stirring, at 80°C, the nitrile thereby going into solution. The reaction mixture was further stirred for 15 minutes at 80°C, cooled and thereafter added dropwise into 200 ml ice water. The precipitated nitro compound was filtered off with suction, washed with a little water and the crude product recyrstallized from acetone. There were obtained 17.2 g (79.9% of theory) 9-(β-cyanoethyl)-3-nitrocarbazole in the form of yellow-green crystals with a melting point of 225°C.

Provenance & Evidence