Borane → HCID 68144932, compound

HRID 268172Notes

Reaction equation

HRID 268172 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]([CH3:12])[C:10](=[O:13])[CH:9]3[CH2:14][CH2:15][CH2:16][N:8]3[C:7](=O)[C:6]=2[CH:18]=1.B>>[F:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]([CH3:12])[C:10](=[O:13])[CH:9]3[CH2:14][CH2:15][CH2:16][N:8]3[CH2:7][C:6]=2[CH:18]=1

Participants

3

Reactant 2

HCID 6331BoraneHCID 12448362HCID 12448362, compound

Product 1

HCID 68144932HCID 68144932, compound

Procedure

When 7-fluoro-1,2,3,11a-tetrahydro-10-methyl-5 H-pyrrolo [2,1-c] [1,4] benzodiazepin- 5,11(10H)-dione (prepared from proline and 5-fluoro N-methylisatoic anhydride as described in Example 1) and borane are reacted as described in Example 1, the above compound is obtained.

Workup

  1. customthe above compound is obtained

Sources & evidence

ORD record
ord-646da63ce1834c3b8a3320594b122076
Source dataset
uspto-grants-1976_03
Patent number
US03947408

Reaction notes

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