Ammonia → HCID 86733181, compound

HRID 268211Notes

Reaction equation

HRID 268211 reaction equation
[C:1]([C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[N:16]=[N:17][CH:18](Br)[C:19]([O:21][CH2:22][CH3:23])=[O:20])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:25]>CCOCC>[C:1]([C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[N:16]=[N:17][CH:18]([NH2:25])[C:19]([O:21][CH2:22][CH3:23])=[O:20])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 54064545HCID 54064545, compound

Product 1

HCID 86733181HCID 86733181, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 8.1 parts of ethyl (2-benzoyl-4-chlorophenylazo)bromoacetate in 16 volume parts of ether is added 160 volume parts of concentrated aqueous ammonia. After stirring the mixture for 1 hour at room temperature, the ether layer is separated, washed with water and evaporated to remove the solvent. The crystalline residue is collected by filtration, washed with ethanol and dried. The procedure gives ethyl (2-benzoyl-4-chlorophenylazo)-aminoacetate. Recrystallization from ethanol gives yellowish orange needles melting at 126°-127°C.

Workup

  1. customthe ether layer is separated
  2. washwashed with water
  3. customevaporated
  4. customto remove the solvent
  5. filtrationThe crystalline residue is collected by filtration
  6. washwashed with ethanol
  7. customdried

Sources & evidence

ORD record
ord-4c9abd12504d47738267feee75a56ae1
Source dataset
uspto-grants-1976_03
Patent number
US03947417

Reaction notes

Loading…