Hydrochloric Acid → HCID 54292768, compound

Participants

Reaction Steps

To a mixture of 15.0 parts of 2-aminobenzophenone, 45 volume parts of acetic acid and 2 volume parts of concentrated hydrochloric acid, a solution of 5.6 parts of sodium nitrite in 16 volume parts of water is added dropwise under ice-cooling and stirring. The mixture is then added dropwise to a solution of 15.0 parts of ethyl β-chloroacetoacetate and 20 parts of potassium acetate in a mixture of 160 volume parts of ethanol and 35 volume parts of water. After 15 minutes precipitated crystals are collected to yield ethyl (2-benzoylphenyl)azochloroacetate as crystals. Recrystallization from ethanol gives yellow needles melting at 119°-120°C.

Provenance & Evidence