1,4-Dibromobutane → 2-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione

HRID 268236Notes

Reaction equation

HRID 268236 reaction equation
Cl.C1C2C(=CC=CC=2)CCN1CCC[CH2:15][N:16]1[C:25](=[O:26])[C:24]2[CH:27]=[CH:28][CH:29]=[C:22]3[C:23]=2[C:18](=[CH:19][CH:20]=[CH:21]3)[C:17]1=[O:30].[Br:31][CH2:32][CH2:33][CH2:34][CH2:35]CBr.BrCCCCBr>>[Br:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:15][N:16]1[C:17](=[O:30])[C:18]2[CH:19]=[CH:20][CH:21]=[C:22]3[C:23]=2[C:24](=[CH:27][CH:28]=[CH:29]3)[C:25]1=[O:26]

Participants

4

Reactant 3

HCID 80561,4-DibromobutaneHCID 81001,5-DibromopentaneHCID 1317101094-(3,4-Dihydro-2(1H)-isoquinolinyl)butyl-1H-benz[de]-isoquinoline-1,3(2H)-dione, hydrochloride

Product 1

HCID 166387912-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione

Procedure

Following the procedure of part (a) of example 39 but substituting 1,5-dibromopentane for the 1,4-dibromobutane, one obtains 2-(5-bromopentyl)-1H-benz[de]isoquinoline-1,3(2H)-dione; m.p. 113°-115°.

Sources & evidence

ORD record
ord-0fa4267b637d4efdb46cc7471ce4e8f5
Source dataset
uspto-grants-1976_03
Patent number
US03947452

Reaction notes

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