Dimethylformamide → HCID 178428207, compound

Participants

Reaction Steps

A stirred reaction mixture of the compound of Example I, C. (22 g., 0.1 mole) and 3-chloro-2-methylaniline (14 g., 0.1 mole) in 200 ml. of dimethylformamide was refluxed for 6 hours. The reaction mixture was stripped in vacuo to yield a tar. Upon standing the tar solidified to give a yellow semisolid. The yellow product was recrystallized twice from methanol/ether to yield 14 g. (37%).

Provenance & Evidence