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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268248Generated: October 27, 2026

4-Bromoaniline → N-(4-bromophenyl)-7-methyl-3H-imidazo[4,5-f]quinolin-9-amine;hydrochloride

https://huagongshe.com/reaction/268248

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromoanilineHCID 7807—
ReactantHCID 178428198HCID 178428198—
SolventEthanolHCID 702—
ProductN-(4-bromophenyl)-7-methyl-3H-imidazo[4,5-f]quinolin-9-amine;hydrochlorideHCID 178428196—

Reaction Steps

A mixture of 37.9 g. (0.174 m.) of the compound of Example I, C., 30 g. (0.174 ml.) of p-bromoaniline and 500 ml. of ethanol was stirred and refluxed overnight. After concentrating in vacuo the residue was recrystallized from 500 m. of MeOH to give 55 g. m.p. 347°-349° .

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03947434
Source datasetuspto-grants-1976_03
ORD IDord-cb5d75acd05842f8b313ecb06aa79be6
Source noteuspto-grants-1976_03