Chloride → HCID 178428233, compound

Participants

Reaction Steps

A mixture of 33 g. (0.15 mole) of the compound of Example I, C. and 21 g. (0.15 mole) of p-dimethylaminoaniline in 1800 ml. of ethanol was refluxed overnight. The solvent was removed by evaporation in vacuo. The residue was recrystallized from ethanol to give 32 g. of yellow solid. The solid was dissolved methyl alcohol and was acidified with a saturated etherhydrogen chloride solution. The product was collected as a cream colored solid and was recrystallized from methyl alcohol to give a yellow solid melting at 210°-215° in a yield of 22 g. (42%). Recrystallization from methyl alcohol raised the melting point to 215°-217°.

Provenance & Evidence