Ethanol → HCID 178493054, compound

HRID 268260Notes

Reaction equation

HRID 268260 reaction equation
Cl.N([C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]3[N:21]=[CH:20][NH:19][C:17]3=2)[N:12]=[C:11]([CH3:22])[CH:10]=1)C1C=CC=CC=1.[Cl:23][C:24]1[C:30]([O:31][CH3:32])=[CH:29][C:27]([NH2:28])=[C:26](OC)[CH:25]=1.[CH2:35]([OH:37])C>>[ClH:23].[Cl:23][C:24]1([O:37][CH3:35])[C:30]([O:31][CH3:32])=[CH:29][C:27]([NH:28][C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[C:16]4[N:21]=[CH:20][NH:19][C:17]4=3)[N:12]=[C:11]([CH3:22])[CH:10]=2)=[CH:26][CH2:25]1

Participants

4

Reactant 3

HCID 702EthanolHCID 228334-Chloro-2,5-dimethoxyanilineHCID 178428198HCID 178428198, compound

Product 1

HCID 178493054HCID 178493054, compound

Procedure

A mixture of 18.5 (0.085 m.) of the compound of Example I, C., 16 g. (0.085 m.) of 4-chloro-2,5-dimethoxyaniline and 250 ml. of ethanol was refluxed with stirring overnight. The solution was concentrated to dryness in vacuo. The crude product was recrystallized from 1000 ml. of MeOH to give 21.5 g., m.p. 274°-277°C.

Workup

  1. concentrationThe solution was concentrated to dryness in vacuo
  2. customThe crude product was recrystallized from 1000 ml
  3. customof MeOH to give 21.5 g

Sources & evidence

ORD record
ord-42684b60e1734f58b8747d1809a1bcd5
Source dataset
uspto-grants-1976_03
Patent number
US03947434

Reaction notes

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