Acetic Anhydride → 4-Methoxyphenyl acetate

HRID 268263Notes

Reaction equation

HRID 268263 reaction equation
[C:1]([O:4][C:5](=[O:7])[CH3:6])(=O)[CH3:2].[CH3:8][O:9][C:10]1[CH:15]=CC(O)=[CH:12][CH:11]=1>>[C:5]([O:4][C:1]1[CH:12]=[CH:11][C:10]([O:9][CH3:8])=[CH:15][CH:2]=1)(=[O:7])[CH3:6]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 90154-Methoxyphenol

Product 1

HCID 709874-Methoxyphenyl acetate

Procedure

To 1500 ml. of acetic anhydride was added portionwise 248 g. (2.0 m) of p-methoxyphenol. Following the addition, the solution was heated on a steam bath for 3 hours, then poured into 5 liters of ice water. The solvents were removed by distillation to give an amber colored liquid weighing 273 g.

Workup

  1. additionthe addition
  2. temperaturethe solution was heated on a steam bath for 3 hours
  3. customThe solvents were removed by distillation
  4. customto give an amber colored liquid

Sources & evidence

ORD record
ord-54b5a517913b4bbab1b7df5c07725241
Source dataset
uspto-grants-1976_03
Patent number
US03947434

Reaction notes

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