反应详情

A mixture of 40 g. (0.184 m.) of the compound of Example I, C., 346 g. (0.184 m.) of 5-chloro-2,4-dimethoxyaniline and 500 ml. of ethanol was refluxed with stirring overnight. The solvents were removed by distillation and the crude product dissolved in 3000 ml. of MeOH. The MeOH filtrate was concentrated to one-half its volume, chilled and filtered to yield 13 g. m.p. 400°.

1. additionA mixture of 40 g
2. customThe solvents were removed by distillation
3. dissolutionthe crude product dissolved in 3000 ml
4. concentrationThe MeOH filtrate was concentrated to one-half its volume
5. temperaturechilled
6. filtrationfiltered
7. customto yield 13 g