反应详情

A mixture containing 14.9 g. (0.1 m) of p-aminopropiophenone 21.7 g. (0.1 m.) of the compound of Example I, C. and 500 ml. of ethanol was refluxed with stirring overnight. It was then concentrated in vacuo to give 34 g. m.p. 287°-289°, complete 320°C. The crude product was recrystallized from 1000 ml. of MeOH to yield 27 g.m.p. softens 318°, melts 328°-330°C.

1. additionA mixture containing 14.9 g
2. concentrationIt was then concentrated in vacuo
3. customto give 34 g
4. customm.p. 287°-289°, complete 320°C
5. customThe crude product was recrystallized from 1000 ml
6. customof MeOH to yield 27 g
7. customsoftens 318°
8. custommelts 328°-330°C.