Hydrogen Bromide → HCID 68132838, compound

Participants

Reaction Steps

The free base isolated from 1.80 g. of rac.-4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoline hydrochloride is stirred for 3 hours with 30 ml. of 48% hydrogen bromide solution at 150° (bath temperature). After concentration and recrystallization from methanol-ether, there is obtained rac.-4-(4-chlorophenyl)-1,2,3,4-tetrahydro-2-methyl-6,7-isoquinolinediol hydrobromide, m.p. 280°-281°.

Provenance & Evidence