p-Anisoyl chloride → 5-Chloro-2-phenyl-3-(4-methoxybenzoyl)benzofuran
Reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[CH:7][C:6]=2[CH:16]=1.[C:17](Cl)(=[O:26])[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[C:7]([C:17](=[O:26])[C:18]3[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=3)[C:6]=2[CH:16]=1Participants
3
Procedure
5-Chloro-2-phenylbenzofuran is acylated with a p-anisoyl chloride according to the procedure described in Example 5 to give 5-chloro-3-(4-methoxybenzoyl)-2-phenylbenzofuran.
Sources & evidence
- ORD record
- ord-59f68bff6d0f4beebcab03f911a318b7
- Source dataset
- uspto-grants-1976_03
- Patent number
- US03947470
Reaction notes
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