Pyridinium chloride → 5-Chloro-3-(4-hydroxybenzoyl)-2-phenylbenzofuran

HRID 268359Notes

Reaction equation

HRID 268359 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[C:7]([C:16](=[O:25])[C:17]3[CH:22]=[CH:21][C:20]([O:23]C)=[CH:19][CH:18]=3)[C:6]=2[CH:26]=1.Cl.N1C=CC=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=3)=[C:7]([C:16](=[O:25])[C:17]3[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=3)[C:6]=2[CH:26]=1

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 214353985-Chloro-2-phenyl-3-(4-methoxybenzoyl)benzofuran

Product 1

HCID 214353365-Chloro-3-(4-hydroxybenzoyl)-2-phenylbenzofuran

Procedure

Demethylation of 5-chloro-3-(4-methoxybenzoyl)-2-phenylbenzofuran with pyridine hydrochloride as described above gives 5-chloro-3-(4-hydroxybenzoyl)-2-phenylbenzofuran.

Sources & evidence

ORD record
ord-636c392b8760460ba86b5bcddea2e93d
Source dataset
uspto-grants-1976_03
Patent number
US03947470

Reaction notes

Loading…