3-Chloropropyl(diethyl)amine → 3-[4-(3-Diethylaminopropoxy)benzoyl]-2-(4-tolyl)benzofuran

HRID 268363Notes

Reaction equation

HRID 268363 reaction equation
[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=2)=[O:7])=[CH:4][CH:3]=1.[CH2:26]([N:28]([CH2:33][CH3:34])[CH2:29][CH2:30][CH2:31]Cl)[CH3:27]>>[CH2:26]([N:28]([CH2:33][CH3:34])[CH2:29][CH2:30][CH2:31][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:18]=[CH:19][C:20]([CH3:23])=[CH:21][CH:22]=2)=[O:7])=[CH:24][CH:25]=1)[CH3:27]

Participants

3

Reactant 2

HCID 669183-Chloropropyl(diethyl)amineHCID 214352683-(4-Hydroxybenzoyl)-2-(4-tolyl)benzofuran

Product 1

HCID 214353563-[4-(3-Diethylaminopropoxy)benzoyl]-2-(4-tolyl)benzofuran

Procedure

Reaction of 3-(4-hydroxybenzoyl)-2-(4-tolyl)benzofuran with 3-diethylaminopropyl chloride by the procedure described in Example 1 gives the title compound.

Sources & evidence

ORD record
ord-a403fa986a0a45a9acac53a60a8c6b0e
Source dataset
uspto-grants-1976_03
Patent number
US03947470

Reaction notes

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