Diethylaminoethyl chloride → 3-[4-(2-Diethylaminoethoxy)benzoyl]-2-(4-tolyl)benzofuran

HRID 268364Notes

Reaction equation

[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=2)=[O:7])=[CH:4][CH:3]=1.[CH2:26]([N:28]([CH2:32][CH3:33])[CH2:29][CH2:30]Cl)[CH3:27]>>[CH2:26]([N:28]([CH2:32][CH3:33])[CH2:29][CH2:30][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([C:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[O:10][C:9]=2[C:17]2[CH:18]=[CH:19][C:20]([CH3:23])=[CH:21][CH:22]=2)=[O:7])=[CH:24][CH:25]=1)[CH3:27]

Participants

Reactant 2

HCID 13364Diethylaminoethyl chloride

HCID 214352683-(4-Hydroxybenzoyl)-2-(4-tolyl)benzofuran

Product 1

HCID 214353993-[4-(2-Diethylaminoethoxy)benzoyl]-2-(4-tolyl)benzofuran

Procedure

Reaction of 3-(4-hydroxybenzoyl)-2-(4-tolyl)benzofuran with 2-diethylaminoethyl chloride by the procedure of Example 1 gives the title compound.

Sources & evidence

ORD record: ord-ca8f706606874909bced733674a75753
Source dataset: uspto-grants-1976_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03947470

Reaction notes

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