p-Anisoyl chloride → HCID 21435298, compound

HRID 268377Notes

Reaction equation

HRID 268377 reaction equation
[F:1][C:2]([F:20])([F:19])[C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][CH:18]=1)[CH2:6][C:7]1[O:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[CH:11]=1.[C:21](Cl)(=[O:30])[C:22]1[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=1>>[CH3:29][O:28][C:25]1[CH:26]=[CH:27][C:22]([C:21]([C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[O:8][C:7]=2[CH2:6][C:5]2[CH:16]=[CH:17][CH:18]=[C:3]([C:2]([F:1])([F:19])[F:20])[CH:4]=2)=[O:30])=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 227688952-{[3-(Trifluoromethyl)phenyl]methyl}-1-benzofuran

Product 1

HCID 21435298HCID 21435298, compound

Procedure

Acylation of 2-(3-trifluoromethylbenzyl)benzofuran with p-anisoyl chloride is carried out as outlined in the procedure of Example 1 to give 3-(4-methoxybenzoyl)-2-(3-trifluoromethylbenzyl)benzofuran.

Sources & evidence

ORD record
ord-b1e717e3b4fb49598064541378c68498
Source dataset
uspto-grants-1976_03
Patent number
US03947470

Reaction notes

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