4-(2-Diethylaminoethoxy)benzoyl chloride hydrochloride → 2-Benzyl-3-[4-(2-diethylaminoethoxy)benzoyl]-4-methoxybenzofuran

HRID 268388Notes

Reaction equation

HRID 268388 reaction equation
[CH2:1]([C:8]1[O:9][C:10]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[C:11]=2[CH:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH2:20]([N:22]([CH2:35][CH3:36])[CH2:23][CH2:24][O:25][C:26]1[CH:34]=[CH:33][C:29]([C:30](Cl)=[O:31])=[CH:28][CH:27]=1)[CH3:21]>>[CH2:1]([C:8]1[O:9][C:10]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[C:11]=2[C:12]=1[C:30](=[O:31])[C:29]1[CH:28]=[CH:27][C:26]([O:25][CH2:24][CH2:23][N:22]([CH2:35][CH3:36])[CH2:20][CH3:21])=[CH:34][CH:33]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 161118754-(2-Diethylaminoethoxy)benzoyl chloride hydrochlorideHCID 214353072-Benzyl-4-methoxybenzofuran

Product 1

HCID 214353372-Benzyl-3-[4-(2-diethylaminoethoxy)benzoyl]-4-methoxybenzofuran

Procedure

Acylation of 2-benzyl-4-methoxybenzofuran with 4-(2-diethylaminoethoxy)benzoyl chloride hydrochloride as described in Example 6 gives 2-benzyl-3-[4-(2-diethylaminoethoxy)benzoyl]-4-methoxybenzofuran.

Sources & evidence

ORD record
ord-26a63c4250a8408095811c9535d6ad17
Source dataset
uspto-grants-1976_03
Patent number
US03947470

Reaction notes

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