HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl isothiocyanate → N-methyl-N'-[2-((4-chloro-2-methyl-5-pyrimidyl)methylthio)ethyl]thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl isothiocyanate | HCID 11167 | — |
| Reactant | 2-(3-Mercaptopropyl)isoindoline-1,3-dione | HCID 11020441 | — |
| Reactant | 2-(Chloromethyl)pyrimidine | HCID 12877371 | — |
| Reactant | N-methyl-N'-[3-(2-pyrimidylmethylthio)propyl]thiourea | HCID 20557895 | — |
| Product | N-methyl-N'-[2-((4-chloro-2-methyl-5-pyrimidyl)methylthio)ethyl]thiourea | HCID 20557890 | — |
Reaction Steps
In the procedure of Example 1(i)(b) and (ii), using 2-chloromethylpyrimidine and 3-phthalimidopropanethiol as the starting materials, the product is N-methyl-N'-[3-(2-pyrimidylmethylthio)propyl]thiourea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04151288 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-ae6c619c6aff412e82c5f563eac1c24f |
| Source note | uspto-grants-1979_04 |