HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 53900511, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3,5-Diethyl-4-hydroxybenzoic acid methyl ester | HCID 54113050 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 53900511 | HCID 53900511 | — |
Reaction Steps
To a cooled solution of 16.2 g. (0.078 mol.) of 3,5-diethyl-4-hydroxybenzoic acid methyl ester and 4.0 g. (0.1 mol.) of sodium hydroxide in 100 ml. of water is added 9.8 g. (7.3 ml., 0.079 mol.) of dimethyl sulfate. The reaction mixture is refluxed for 2 hours. After cooling, ether is added and the layers are separated. The organic phase is washed with water, dilute sulfuric acid and water, dried (Na2SO4) and concentrated to give 3,5-diethyl-4-methoxybenzoic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03947470 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-f9fa7b4dbd8b424b97fef61656888c76 |
| Source note | uspto-grants-1976_03 |