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5,6,7,8-Tetrahydro-1-naphthol → 4-(2-Methylphenyl)-1-[3-(5,6,7,8-tetrahydronaphth-1-yloxy)-prop-1-yl]-piperazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5,6,7,8-Tetrahydro-1-naphthol | HCID 68258 | — |
| 反応物 | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| 反応物 | 1-(3-Chloropropyl)-4-(2-methoxyphenyl)piperazine | HCID 622669 | — |
| 反応物 | 1-[3-(5,6,7,8-Tetrahydronaphth-1-yloxy)-propyl]-4-(2-methoxyphenyl)-piperazine | HCID 21551666 | — |
| 生成物 | 4-(2-Methylphenyl)-1-[3-(5,6,7,8-tetrahydronaphth-1-yloxy)-prop-1-yl]-piperazine | HCID 21551655 | — |
反応手順
1-[3-(5,6,7,8-tetrahydronaphth-1-yloxy)-propyl]-4-(2-methoxyphenyl)-piperazine from 5,6,7,8-tetrahydro-1-naphthol and 1-(3-chloropropyl)-4-(2-methoxyphenyl)-piperazine; yield 48% of theory; m.p. of the dihydrochloride 202°-203°C. (decomp.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03947446 |
| 出典データセット | uspto-grants-1976_03 |
| ORD ID | ord-8424f0045f994d0b8436c23596582853 |
| 出典メモ | uspto-grants-1976_03 |