HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitrobutane → 3-(2'-Methyl-2'-aminopentyl)-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitrobutane | HCID 11749 | — |
| Reactant | 2-Nitropentane | HCID 145756 | — |
| Reactant | 3-(2'-Methyl-2'-nitropentyl)-indole | HCID 21552230 | — |
| Product | 3-(2'-Methyl-2'-aminopentyl)-indole | HCID 21552249 | — |
Reaction Steps
If the 2-nitrobutane in Example 1 is replaced by the corresponding quantity of 2-nitropentane, using the same procedure as in Example 1, the intermediate product obtained is 3-(2'-methyl-2'-nitropentyl)-indole; melting point 78°-80°C (from petroleum ether). Reduction yielded 3-(2'-methyl-2'-aminopentyl)-indole, which after recrystallisation from petroleum ether yields needle-shaped crystals of a melting point of 73.5° to 74.5°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03947584 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-4380c599b30e4fd589d8d50ad317959a |
| Source note | uspto-grants-1976_03 |