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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268491Generated: October 30, 2026

HCID 21413805, compound → 4-(5,7-Dichlorobenzoxazol-2-yl)phenylacetonitrile

https://huagongshe.com/reaction/268491

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21413805HCID 21413805—
Reactant5,7-Dichloro-2-(4-bromomethylphenyl)benzoxazoleHCID 21413820—
Reactant7-Chloro-2-(4-bromomethylphenyl)benzoxazoleHCID 21413859—
Reactant4-(Benzoxazol-2-yl)-1-bromobenzocyclobuteneHCID 131710118—
Product4-(5,7-Dichlorobenzoxazol-2-yl)phenylacetonitrileHCID 21413851—
Product4-(7-Chlorobenzoxazol-2-yl)-phenylacetonitrileHCID 21413858—
Product4-(Benzoxazol-2-yl)-1-cyanobenzocyclobuteneHCID 131710117—

Reaction Steps

When 7-chloro-2-(4-bromomethylphenyl)benzoxazole, 5,7-dichloro-2-(4-bromomethylphenyl)benzoxazole and 4-(benzoxazole-2-yl)-1-bromobenzocyclobutene are used in place of 2-(4-bromomethyl-3-fluorophenyl)benzoxazole in the above example, there is obtained 4-(7-chlorobenzoxazol-2-yl)-phenylacetonitrile, 4-(5,7-dichlorobenzoxazol-2-yl)phenyl-acetonitrile, and 4-(benzoxazol-2-yl)-1-cyanobenzocyclobutene, respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03947582
Source datasetuspto-grants-1976_03
ORD IDord-2bf0923a7ef04152801c986a649e888a
Source noteuspto-grants-1976_03