Sulfuric Acid → HCID 21413842, compound

HRID 268501Notes

Reaction equation

HRID 268501 reaction equation
[C:1]([C:4]1[CH:15]=[CH:14][C:7]([C:8](O)([CH3:12])[C:9]([NH2:11])=[O:10])=[CH:6][CH:5]=1)([OH:3])=[O:2].S(=O)(=O)(O)O>C(O)(=O)C>[C:1]([C:4]1[CH:15]=[CH:14][C:7]([C:8](=[CH2:12])[C:9]([NH2:11])=[O:10])=[CH:6][CH:5]=1)([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 21413802HCID 21413802, compound

Product 1

HCID 21413842HCID 21413842, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a solution of 0.05 moles of p-carboxy-α-hydroxyhydratropamide in 50 cc. of acetic acid is added 5 cc. of a concentrated sulfuric acid. The mixture is heated on the steam-bath for 1/2 hour, then concentrated in vacuo. Addition of water to the residue and filtration gives p-carboxyatropamide.

Workup

  1. temperatureThe mixture is heated on the steam-bath for 1/2 hour
  2. concentrationconcentrated in vacuo
  3. additionAddition of water
  4. filtrationto the residue and filtration

Sources & evidence

ORD record
ord-2a3a681edbce4888a3a742e1901cb86a
Source dataset
uspto-grants-1976_03
Patent number
US03947582

Reaction notes

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