Oxygen → HCID 515320, compound

Participants

Reaction Steps

A solution of 12.0 g (0.025 mole) 2,7-bis(5-diethylaminovaleryl)fluorene, prepared in Example 29, 2.0 ml 40% benzyltrimethylammonium hydroxide in pyridine and 200 ml pyridine is stirred at room temperature while oxygen is bubbled through the solution at a rate of 500 ml/min. for a total of four hours. The reaction mixture is evaporated to dryness leaving a residue which is chromatographed on alumina using chloroform as the eluant. The solvent is removed from the reaction collected leaving a solid which is recrystallized once from chloroform-petroleum ether to yield 2,7-bis(5-diethylaminovaleryl)fluoren-9-one. M.P. 108°-109.5°C.

Provenance & Evidence