HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 20361351, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | HCID 21551926 | HCID 21551926 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 20361351 | HCID 20361351 | — |
Reaction Steps
In the manner given in Example 23, a solution of 8-chloro-1-(aminomethyl)-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in acetonitrile is treated with formalin, sodium cyanoborohydride and acetic acid to give 8-chloro-1-[(dimethylamino)methyl]-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03947466 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-74a6b2f2c29f4ec2b0066d3efc44135c |
| Source note | uspto-grants-1976_03 |