Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69218359, compound

HRID 268556Notes

Reaction equation

HRID 268556 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][OH:17])=[CH:6][C:5]=1[CH3:18])([O-])=O.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:31].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:31].[ClH:31].[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][OH:17])=[CH:6][C:5]=1[CH3:18]

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 23104289HCID 23104289, compound

Product 1

HCID 69218359HCID 69218359, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 6-(4-nitro-3-methylphenylamino)hexan-1-ol (9) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-f2fbc9e7b6394c58b4a7708278c51d8b
Source dataset
uspto-grants-2008_11
Patent number
US07445645B2

Reaction notes

Loading…