Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69221718, compound

HRID 268557Notes

Reaction equation

HRID 268557 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][OH:17])=[C:6]([CH3:18])[CH:5]=1)([O-])=O.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:31].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:31].[ClH:31].[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][OH:17])=[C:6]([CH3:18])[CH:5]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 23104287HCID 23104287, compound

Product 1

HCID 69221718HCID 69221718, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 6-(4-nitro-2-methylphenylamino)hexan-1-ol (11) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-7cbd82677ee4439ca0020ff526db9f1b
Source dataset
uspto-grants-2008_11
Patent number
US07445645B2

Reaction notes

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