HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268564Generated: October 29, 2026
Potassium Carbonate → HCID 23104305, compound
https://huagongshe.com/reaction/268564
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | Benzene, 1-fluoro-2-methyl-4-nitro- | HCID 68001 | — |
| Reactant | 5-Aminopentan-1-ol | HCID 75634 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 23104305 | HCID 23104305 | 94.4% |
Reaction Steps
2 g of 2-fluoro-5-nitrotoluene were added to a solution of 20 ml of N-methylpyrrolidinone, 1.6 g of 5-amino-1-pentanol and 2.14 g of K2CO3. The reaction medium was heated at 60° C. for 12 hours and, after cooling to room temperature, was then poured into a water and ice mixture. The yellow precipitate formed was filtered off, reslurried in water and then dried over P2O5. 2.9 g of 5-(4-nitro-2-methylphenylamino)pentan-1-ol (19) were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07445645B2 |
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| Source dataset | uspto-grants-2008_11 |
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| ORD ID | ord-c2bace3e4feb44cd8f49a2990e9ef7f7 |
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| Source note | uspto-grants-2008_11 |
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