HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrafluoro-m-phenylenediamine dihydrochloride → 4-(4-Amino-2-methylphenylamino)butan-2-ol dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| Reactant | 4-(4-Nitro-2-methylphenylamino)butan-2-ol | HCID 23104308 | — |
| Catalyst | ZINC ammonium chloride water ethanol | HCID 131726756 | — |
| Product | 4-(4-Amino-2-methylphenylamino)butan-2-ol dihydrochloride | HCID 69221355 | — |
Reaction Steps
The 4-(4-nitro-2-methylphenylamino)butan-2-ol (27) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07445645B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-4c11cee63ef64e76bcba09e523cf8b54 |
| Source note | uspto-grants-2008_11 |