HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrafluoro-m-phenylenediamine dihydrochloride → 4-(4-Amino-3-methylphenylamino)butan-2-ol dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| Reactant | 4-(4-Nitro-3-methylphenylamino)butan-2-ol | HCID 23104300 | — |
| Catalyst | ZINC ammonium chloride water ethanol | HCID 131726756 | — |
| Product | 4-(4-Amino-3-methylphenylamino)butan-2-ol dihydrochloride | HCID 69220474 | — |
Reaction Steps
The 4-(4-nitro-3-methylphenylamino)butan-2-ol (31) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07445645B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-27288e91282f4737b90e6298ba645bfe |
| Source note | uspto-grants-2008_11 |