1-Benzyl-4-piperidylamine → HCID 58715029, compound

HRID 268606Notes

Reaction equation

HRID 268606 reaction equation
[CH3:1][C:2]([O:5][C:6]([N:8]1[C@H:17]([C:18]([OH:20])=O)[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9]1)=[O:7])([CH3:4])[CH3:3].[NH2:21][CH:22]1[CH2:27][CH2:26][N:25]([CH2:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH2:24][CH2:23]1>>[C:2]([O:5][C:6]([N:8]1[C@H:17]([C:18](=[O:20])[NH:21][CH:22]2[CH2:27][CH2:26][N:25]([CH2:28][C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[CH2:24][CH2:23]2)[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:1]

Participants

3

Reactant 2

HCID 4158521-Benzyl-4-piperidylamineHCID 664088(3S)-2-((tert-butoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

Product 1

HCID 58715029HCID 58715029, compound

Procedure

Compound 1c was prepared from N-Boc-L-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and 4-amino-1-benzylpiperidine, using the method described in Example 1.

Sources & evidence

ORD record
ord-08a99f5a954f46fb91ef747dd2bda81c
Source dataset
uspto-grants-2008_11
Patent number
US07446115B2

Reaction notes

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