Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268657Generated: October 29, 2026

4-Carboxyphenylboronic Acid → 4-[1-Ethyl-1-(2-hydroxy-ethyl)-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-8-yl]-benzoic acid

https://huagongshe.com/reaction/268657

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Carboxyphenylboronic AcidHCID 312183—
Reactant2-(8-Bromo-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-ethanolHCID 69196696—
Product4-[1-Ethyl-1-(2-hydroxy-ethyl)-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-8-yl]-benzoic acidHCID 11486609—

Reaction Steps

The title compound is prepared in a manner analogous to Example 1, except using 2-(8-bromo-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-ethanol and 4-carboxylphenylboronic acid in step 1.F.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446122B2
Source datasetuspto-grants-2008_11
ORD IDord-7d8a33f1677c43ecbc643b271971edcb
Source noteuspto-grants-2008_11