Dibenzofuran-4-boronic acid → 2-(8-Dibenzofuran-3-YL-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-B]indol-1-YL)-ethanol

HRID 268660Notes

Reaction equation

HRID 268660 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:20]([CH3:22])[CH3:21])[CH:5]=[C:6]2[C:10]=1[NH:9][C:8]1[C:11]([CH2:17][CH2:18][OH:19])([CH2:15][CH3:16])[O:12][CH2:13][CH2:14][C:7]2=1.[CH:23]1[C:31]2[C:30]3[CH:32]=[CH:33][CH:34]=[CH:35][C:29]=3[O:28][C:27]=2[C:26](B(O)O)=[CH:25][CH:24]=1>>[CH:23]1[C:31]2[C:30]3[CH:32]=[CH:33][CH:34]=[CH:35][C:29]=3[O:28][C:27]=2[CH:26]=[C:25]([C:2]2[CH:3]=[C:4]([CH:20]([CH3:21])[CH3:22])[CH:5]=[C:6]3[C:10]=2[NH:9][C:8]2[C:11]([CH2:17][CH2:18][OH:19])([CH2:15][CH3:16])[O:12][CH2:13][CH2:14][C:7]3=2)[CH:24]=1

Participants

3

Reactant 2

HCID 2734328Dibenzofuran-4-boronic acidHCID 691966962-(8-Bromo-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-ethanol

Product 1

HCID 114083952-(8-Dibenzofuran-3-YL-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-B]indol-1-YL)-ethanol

Procedure

The title compound is prepared in a manner analogous to Example 1, except using 2-(8-bromo-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-ethanol and 4-dibenzofuranboronic acid in step 1.F.

Sources & evidence

ORD record
ord-b43ae560bea74330a358b9d94701c6c8
Source dataset
uspto-grants-2008_11
Patent number
US07446122B2

Reaction notes

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