HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tryptophol → 8'-Ethyl-4',9'-dihydro-3'H-spiro(cyclohexane-1,1'-pyrano[3,4-b]indole)-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tryptophol | HCID 10685 | — |
| Reactant | 7-Ethyltryptophol | HCID 198231 | — |
| Reactant | Ethyl 4-oxocyclohexanecarboxylate | HCID 317638 | — |
| Product | 8'-Ethyl-4',9'-dihydro-3'H-spiro(cyclohexane-1,1'-pyrano[3,4-b]indole)-4-carboxylic acid ethyl ester | HCID 69196892 | — |
Reaction Steps
Following the procedure of example 24.A. except using 2-(7-ethyl-1H-indol-3-yl)-ethanol as the 3-indolethanol component and 4-oxo-cyclohexane carboxylic acid ethyl ester as ketone component afforded the title compound as an oil. ESI (+) MS m/e=342 (MH+), ESI (−) MS m/e=340 (MH−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446122B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-5b0693fdf6b9439d8229470b8343cdf3 |
| Source note | uspto-grants-2008_11 |