HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268672Generated: October 30, 2026
Sulfuric Acid → 7-Isopropylindoline-2,3-dione
https://huagongshe.com/reaction/268672
Participants
| Role | Name | HCID | Charge |
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| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2-(Hydroxyimino)-N-[2-(propan-2-yl)phenyl]acetamide | HCID 71443947 | — |
| Product | 7-Isopropylindoline-2,3-dione | HCID 12272793 | 84% |
Reaction Steps
To concentrated sulfuric acid at 80° C. was added 2-hydroxyimino-N-(2-isopropyl-phenyl)-acetamide in several small portions over 10 minutes. After addition it was heated at 80° C. for 30 minutes., then poured into ice. Filtration, washing with water, and drying under vacuum over P2O5 provided 2.974 g (84%) of the title compound as a solid. ESI (−) MS m/e=188 (MH−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07446122B2 |
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| Source dataset | uspto-grants-2008_11 |
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| ORD ID | ord-fed303f8340645ab8a55b2ebef99768f |
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| Source note | uspto-grants-2008_11 |
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