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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268675Generated: October 26, 2026

Acetamide → 7-Trifluoromethylisatin

https://huagongshe.com/reaction/268675

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetamideHCID 178—
Reactant2-hydroxyimino-N-(2-trifluoromethyl-phenyl)-acetamideHCID 78408200—
Product7-TrifluoromethylisatinHCID 604575—

Reaction Steps

Following the procedure of example 36.B. except using 2-hydroxyimino-N-(2-trifluoromethyl-phenyl)-acetamide as the acetamide component afforded the title compound as a solid. ESI (−) MS m/e=214 (MH−).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446122B2
Source datasetuspto-grants-2008_11
ORD IDord-9265472fc82e4e1fac61141540978b54
Source noteuspto-grants-2008_11