Acetamide → 5-Bromo-7-ethylindoline-2,3-dione

HRID 268677Notes

Reaction equation

HRID 268677 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:13])[CH:10]=NO)=[C:4]([CH2:14][CH3:15])[CH:3]=1.C(N)(=[O:18])C>>[Br:1][C:2]1[CH:7]=[C:6]2[C:5](=[C:4]([CH2:14][CH3:15])[CH:3]=1)[NH:8][C:9](=[O:13])[C:10]2=[O:18]

Participants

3

Reactant 2

HCID 178AcetamideHCID 86041545N-(4-Bromo-2-ethyl-phenyl)-2-hydroxyimino-acetamide

Product 1

HCID 80338135-Bromo-7-ethylindoline-2,3-dione

Procedure

Following the procedure of example 36.B. except using N-(4-Bromo-2-ethyl-phenyl)-2-hydroxyimino-acetamide as the acetamide component afforded the title compound as a solid. ESI (−) MS m/e=252 (MH−).

Sources & evidence

ORD record
ord-8bb24b8c0c7a4715bec27885249914e8
Source dataset
uspto-grants-2008_11
Patent number
US07446122B2

Reaction notes

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