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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268728Generated: October 25, 2026

5-Fluoro-2-methylindole → 5-Fluoro-2-methyl-N-[4-(3-piperidin-1-ylpropoxy)benzoyl]-indole hydrochloride

https://huagongshe.com/reaction/268728

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Fluoro-2-methylindoleHCID 2778715—
Reactant4-(3-Piperidin-1-ylpropoxy)benzoic acid hydrochlorideHCID 68963614—
Product5-Fluoro-2-methyl-N-[4-(3-piperidin-1-ylpropoxy)benzoyl]-indole hydrochlorideHCID 17986304—

Reaction Steps

The title compound (E6) was prepared from 4-(3-piperidin-1-ylpropoxy)benzoic acid hydrochloride (D2) and 5-fluoro-2-methyl-indole using the method described in Example 5 (E5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446103B2
Source datasetuspto-grants-2008_11
ORD IDord-838ab7e535e948debd687977c41fd5ce
Source noteuspto-grants-2008_11