HCID 59831668, compound → HCID 59831648, compound

HRID 268757Notes

Reaction equation

HRID 268757 reaction equation
N1C2C(=CC=C(C(C3C=CC=CC=3)CCN)C=2)C=C1.[CH3:20][O:21][C:22](=[O:42])[NH:23][CH2:24][CH2:25][CH:26]([C:33]1[CH:41]=[CH:40][CH:39]=[C:38]2[C:34]=1[CH:35]=[CH:36][NH:37]2)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH3:20][O:21][C:22](=[O:42])[NH:23][CH2:24][CH2:25][CH:26]([C:33]1[CH:34]=[C:38]2[C:39]([CH:35]=[CH:36][NH:37]2)=[CH:40][CH:41]=1)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1

Participants

3

Reactant 2

HCID 59831668HCID 59831668, compoundHCID 59831919HCID 59831919, compound

Product 1

HCID 59831648HCID 59831648, compoundYield 89%

Procedure

[3-(1H-Indol-6-yl)-3-phenyl-propyl]-carbamic acid methylester XV (0.554 g, 89% yield) was prepared from 3-(1H-indol-6-yl)-3-phenyl-propylamine using the procedure described for [3-(1H-indol-4-yl)-3-phenyl-propyl]-carbamic acid methylester V (see Example 1).

Sources & evidence

ORD record
ord-b643c91a95654838b76f67bdd8535f6e
Source dataset
uspto-grants-2008_11
Patent number
US07446118B2

Reaction notes

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