[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine → HCID 59831656, compound

HRID 268782Notes

Reaction equation

HRID 268782 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:10]([C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[CH:17]=3)[CH2:11][C:12]([NH:14][CH3:15])=O)[CH:8]=2)[CH:3]=[CH:2]1.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CCNC)C=C1>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:10]([C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[CH:17]=3)[CH2:11][CH2:12][NH:14][CH3:15])[CH:8]=2)[CH:3]=[CH:2]1

Participants

3

Reactant 2

HCID 17747555[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amineHCID 59831880HCID 59831880, compound

Product 1

HCID 59831656HCID 59831656, compound

Procedure

[3-(1H-Indol-6-yl)-3-(3-chloro-phenyl)-propyl]-methyl-amine XLII was prepared as a hydrochloride salt (190 mg, 83% yield) from 3-(1H-indol-6-yl)-3-(3-chloro-phenyl)-N-methyl-propionamide, using the procedure described above for [3-(1H-indol-7-yl)-3-phenyl-propyl]-methyl-amine XX (see Example 4). MS (M+H)=299.

Sources & evidence

ORD record
ord-8b2788b2b45e4548af5185c5071b3e37
Source dataset
uspto-grants-2008_11
Patent number
US07446118B2

Reaction notes

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