Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268804Generated: October 25, 2026

3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester → HCID 67355796, compound

https://huagongshe.com/reaction/268804

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl esterHCID 67355322—
Reactant3-(3-Methyl-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl esterHCID 67356025—
ProductHCID 67355796HCID 6735579662%

Reaction Steps

N-Methyl-3-(3-methyl-1H-indol-5-yl)-3-phenyl-acrylamide LXXII (386 mg, 62% yield) was prepared from 3-(3-methyl-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl ester using the procedure described above for preparation of 3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester XVIII (see Example 4).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446118B2
Source datasetuspto-grants-2008_11
ORD IDord-e511cecac88a4e989fdbf41471ccd55b
Source noteuspto-grants-2008_11